Chao (Oliver) Xu

Chao (Oliver) Xu

Think in the future

Welcome to my page! I am Chao (Oliver) Xu. Currently, I work at Department of Biomedical Engineering, The Chinese University of Hong Kong, as a research assistant, affiliated with the Advanced Biomedical Imaging Laboratory.

During my postgraduate period, I mainly focused on minimally invasive high-resolution endoscopic optical coherence tomography (OCT) and its preclinical applications. Currently, I am working on the high-resolution intravascular OCT for clinical use. I am also developing some advanced fabrication technology for high-performance OCT endoscopy.

I graduated from College of Optical Science and Engineering, Zhejiang University with a bachelor’s degree and from Daheng College, University of Chinese Academy of Sciences with a Master’s degree. I further obtained my doctor’s degree from Department of Biomedical Engineering, The Chinese University of Hong Kong, advised by Prof. Wu (Scott) Yuan (袁武).

My research interest includes high-resolution OCT, optical endomicroscopy, and preclinical /clinical applications related with OCT. I have published 17 papers at the top international journals such as Nature Communications, APL Photonics, and Communications Engineering.

🔥 News

  • 2024.11:  🎉🎉 One paper about first submillimeter visible-light OCT neuroendoscopy is accepted by APL Photonics.
  • 2024.10:  🎉🎉 Congratulations to Dr.Xu for starting with his new career life!
  • 2024.09:  🎉🎉 One paper about wearable OCT neuroendoscopy is accepted by Advanced Intelligent Systems.
  • 2024.09:  🎉🎉 One paper about magnetic force-driven OCT endoscope is accepted by Nature Communications.
  • 2024.07:  🎉🎉 I pass my Ph.D. thesis defense at The Chinese University of Hong Kong!
  • 2024.01:  🎉🎉 One paper about liquid shaping technique to fabricate miniature high-resolution OCT endoscope is accepted by Communications Engineering.
  • 2023.08:  🎉🎉 One paper about digitally compensating dispersion of OCT system is accepted by Photonics.

📝 Publications

Peer Reviewed Journal Publications

  1. C. Xu, T. Zhang, S. A. Abbasi, P. Liu, B. P. Yan, S.H.C. Ng, W. Yuan, Ultrathin visible-light OCT endomicroscopy for in vivo ultrahigh-resolution neuroimaging in deep brain. APL Photonics 9, 110804 (2024).

  2. C. Xu+, Z. Fang+, H. Gao, T. Zhang, T. Zhang, P. Liu, H. Ren, W. Yuan, Patient‐mounted neuro optical coherence tomography for targeted minimally invasive micro‐resolution volumetric imaging in brain in vivo. Advanced Intelligent Systems, 2400488 (2024). (+: equal contribution)

  3. S. Yuan+, C. Xu+, B. Cui+, T. Zhang, B. Liang, W. Yuan, H. Ren, Motor-free telerobotic endomicroscopy with steerable and programmable imaging in complex curved and localized areas. Nature Communications 15, 1–16 (2024). (+: equal contribution).

  4. T. Zhang, S. Yuan, C. Xu, P. Liu, H. C. Chang, S. H. C. Ng, H. Ren, W. Yuan, PneumaOCT: pneumatic optical coherence tomography endoscopy for targeted distortion-free imaging in tortuous and narrow internal lumens. Science Advances 10, eadp3145 (2024).

  5. C. Xu, X. Guan, S. A. Abbasi, N. Xia, T. Ngai, L. Zhang, H.-P. Ho, S. H. C. Ng, W. Yuan, Liquid-shaped microlens for scalable production of ultrahigh- resolution optical coherence tomography microendoscope. Communications Engineering 3, 1 (2024).

  6. J. Wang+, C. Xu+, S. Zhu, D. Chen, H. Qiu, A. K. N. Lam, C. K. S. Leung, W. Yuan, A Generic and effective system dispersion compensation method: development and validation in visible-light OCT. Photonics 10, 892 (2023). (+: equal contribution)

Conference Papers

  1. C. Xu, T. Zhang, R. Zhang, W. Yuan, “In Vivo Ultrahigh-Resolution Quantitative OCT Imaging in Lungs,” 2024 IEEE International Conference on Consumer Electronics-Asia (ICCE-Asia), Danang, Vietnam, 2024, pp. 1-4.

  2. C. Xu, Z. Hong, R. Liang, W. Yuan, “3D printed freeform silica microlens for ultrathin high-performance OCT endoscopy” in Frontiers in Optics + Laser Science 2024 (FiO, LS) (2024), Paper FM4D.3 (Optica Publishing Group, 2024), p. FM4D.3.

  3. C. Xu, T. Zhang, P. Liu, W. Yuan, “Aberration-corrected high-resolution OCT microprobe using liquid-shaped freeform microlens” in Frontiers in Optics + Laser Science 2024 (FiO, LS) (2024), Paper FM3D.6 (Optica Publishing Group, 2024), p. FM3D.6.

  4. C. Xu, T. Zhang, P. Liu, W. Yuan, “Miniature ultrahigh-resolution visible-light OCT endoscopy” in Endoscopic Microscopy XIX, M. J. Suter, G. J. Tearney, T. D. Wang, Eds. (2024) vol. 12820, p. 27.

  5. C. Xu, Z. Fang, T. Zhang, H. Gao, T. Zhang, P. Liu, H. Ren, W. Yuan, “Submillimeter robotic OCT neuroendoscope for deep-brain imaging in vivo” in Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXII (2024) vol. 12831, pp. 5–8.

  6. J. Yan, P. Chen, J. Chen, J. Xue, C. Xu, Y. Qiu, H. Fang, Y. Lu, G. K. C. Wong, Y.-H. Liu, W. Yuan, S. S. Cheng, “Design and evaluation of a flexible sensorized robotic OCT neuroendoscope” in 2023 International Symposium on Medical Robotics (ISMR) (2023) pp. 1–7.

  7. J. Wang, C. Xu, S. Zhu, W. Yuan, “An optimization method for ultrahigh-resolution vis-OCT imaging” in TENCON 2022 - 2022 IEEE Region 10 Conference (TENCON) (2022), pp. 1–3.

Patents

  1. Systems and methods for scalable fabrication of high-performance optical coherence tomography endoscopes using liquid shaping technique. US patent. No. 18/775,087. Second-inventor (supervisor as first inventor).

  2. 可扩展地制造高性能光学相干断层扫描内窥镜系统和方法. CN202410901042.6. 第二发明人(导师为第一发明人).

  3. 一种高频颤振扰动光学TDI相机成像的模拟系统. CN109632261B. 第二发明人(导师为第一发明人).

  4. 卫星对动态飞行目标多视角成像联合计算航行高度的方法. CN201910761722.1. 第三发明人.

  5. 空间脉管包络分布式三维目标的卫星成像路径规划方法. CN109738928A. 第四发明人.

  6. 双线阵TDI空间相机对动态飞机运动特性的分析方法. CN108961319A. 第四发明人.

  7. TDI CCD相机摆扫成像影像几何畸变还原的反变换方法. CN108898565A. 第五发明人.

  8. 基于改进BM3D算法的图像去噪方法及系统. CN110060220A. 第六发明人.

🎖 Honors and Awards

  • Hong Kong Medical and Healthcare Device Industries Association Student Research Award, 2024
  • Outstanding Graduate of the University of Chinese Academy of Sciences, 2020
  • New Industry Scholarship, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, 2020
  • National Scholarship, 2019
  • Merit Student Award, University of Chinese Academy of Sciences, 2019
  • Merit Student Award, University of Chinese Academy of Sciences, 2018
  • Freshman Scholarship, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, 2017

📖 Educations

  • 2021.01 - 2024.10, Doctor of Philosophy, Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China
  • 2017.09 - 2020.07, Master of Science, Daheng College, University of Chinese Academy of Sciences, Beijing, China.
  • 2013.09 - 2017.07, Bachelor of Engineering, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China.

💬 Invited Talks

💻 Internships